QuickLinks -- Click here to rapidly navigate through this document

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549


FORM 8-A

FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934


BIOSANTE PHARMACEUTICALS, INC.
(Exact Name of Registrant as Specified in its Charter)

Delaware   58-2301143
(State or Other Jurisdiction of Incorporation)   (I.R.S. Employer Identification Number)

111 Barclay Boulevard

 

 
Lincolnshire, Illinois   60069
(Address of Principal Executive Offices)   (Zip Code)

        If this form relates to the registration of a class of securities pursuant to Section 12(b) of the Exchange Act and is effective pursuant to General Instruction A.(c), check the following box: ý

        If this form relates to the registration of a class of securities pursuant to Section 12(g) of the Exchange Act and is effective pursuant to General Instruction A.(d), check the following box: o

Securities Act registration statement file number to which this form relates: Not applicable

Securities to be registered pursuant to Section 12(b) of the Act:

Title of Each Class   Name of Each Exchange on Which
to be so Registered
  Each Class is to be Registered
Common Stock, par value $0.0001   The American Stock Exchange

Securities to be registered pursuant to Section 12(g) of the Act: None




Item 1. Description of Registrant's Securities to Be Registered

The description of the registrant's common stock, par value $0.0001 per share, is incorporated by reference to the material under the section "Description of Capital Stock" in the registrant's registration statement on Form SB-2 as filed with the Securities and Exchange Commission on September 5, 2003, as amended, Commission Reg. No. 333-108550.

Item 2. Exhibits.

Exhibit
No.

  Description

3.1

 

Amended and Restated Certificate of Incorporation of BioSante Pharmaceuticals, Inc.

3.2

 

Amendment to Amended and Restated Certificate of Incorporation of BioSante Pharmaceuticals, Inc.

3.3

 

Bylaws of BioSante Pharmaceuticals, Inc.

2



SIGNATURE

        Pursuant to the requirements of Section 12 of the Securities Exchange Act of 1934, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized.

    BIOSANTE PHARMACEUTICALS, INC.

 

 

By:

/s/ STEPHEN M. SIMES

Stephen M. Simes
President and Chief Executive Officer

Dated: September 25, 2003

 

 

 

3


BIOSANTE PHARMACEUTICALS, INC.

REGISTRATION STATEMENT ON FORM 8-A

INDEX TO EXHIBITS

Exhibit
No.

  Description
  Method of Filing

3.1

 

Amended and Restated Certificate of Incorporation of BioSante Pharmaceuticals, Inc.

 

Incorporated by reference to Exhibit 3.1 contained in BioSante's Registration Statement on Form SB-2 (Reg. No. 333-64218)

3.2

 

Amendment to Amended and Restated Certificate of Incorporation of BioSante Pharmaceuticals, Inc.

 

Filed herewith electronically

3.3

 

Bylaws of BioSante Pharmaceuticals, Inc.

 

Incorporated by reference to Exhibit 3.2 contained in BioSante's Registration Statement on Form SB-2 (Reg. No. 333-64218)

4




QuickLinks

SIGNATURE

QuickLinks -- Click here to rapidly navigate through this document


EXHIBIT 3.2


CERTIFICATE OF AMENDMENT
OF THE
AMENDED AND RESTATED CERTIFICATE OF INCORPORATION
OF BIOSANTE PHARMACEUTICALS, INC.

        BioSante Pharmaceuticals, Inc., a corporation organized and existing under and by virtue of the laws of State of Delaware (the "Corporation"), pursuant to the provisions of the General Corporation Law of State of Delaware (the "DGCL"), DOES HEREBY CERTIFY that:

        FIRST: The Board of Directors of the Corporation, at meetings held on April 16, 2002 and May 21, 2002, duly adopted resolutions setting forth proposed amendments of the Amended and Restated Certificate of Incorporation of the Corporation, declaring said amendments to be advisable and proposing that said amendments be submitted to the stockholders of the Corporation for their consideration and approval. The resolutions setting forth the proposed amendments are substantially as follows:


        SECOND: The stockholders of the Corporation duly approved and adopted such amendments in accordance with the provisions of Section 242 of the DGCL by a vote of the holders of a majority of the shares of outstanding Common Stock and the holders of a majority of the shares of outstanding Class C Special Stock of the Corporation entitled to vote thereon at the annual meeting of stockholders duly held on May 21, 2002, upon notice in accordance with Section 222 of the DGCL.


        IN WITNESS WHEREOF, the Corporation has caused this Certificate of Amendment to be signed by Stephen M. Simes, its President and Chief Executive Officer, thereunto duly authorized, this 30th day of May, 2002.

    BIOSANTE PHARMACEUTICALS, INC.

 

 

By:

/s/ STEPHEN M. SIMES

Stephen M. Simes
Vice Chairman, President and
Chief Executive Officer



QuickLinks

CERTIFICATE OF AMENDMENT OF THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF BIOSANTE PHARMACEUTICALS, INC.