United States securities and exchange commission logo January 30, 2023 Stephen P. Carey Senior Vice President, Finance and Chief Financial Officer ANI Pharmaceuticals, Inc. 210 Main Street West Baudette , Minnesota 56623 Re: ANI Pharmaceuticals, Inc. Form 10-K for Fiscal Year Ended December 31, 2021 Filed March 15, 2022 File No. 001-31812 Dear Stephen P. Carey: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences